SpRYCas9 is an RNA-mediated nuclease, which can catalyze the specific site cleavage of double-stranded DNA. It can recognize NNN (NRN > NYN) PAM sequence, which almost gets rid of the restriction of the PAM.
Cat. No.: Cas9NNN-70 (for 70pmol)
Cat. No.: Cas9NNN-2k (for 2000pmol)
Compared with the mRNA or plasmid systems:
Transcription and translation processes are not required
Avoiding the risk of inserting foreign DNA into the genome
Minimizing the off-target effect
in vitro cleavage assay
RNP complex transfection
Recommended to be stored at -20°C.
Only for research and not intended for treatment of humans or animals