LwCas13a, belonging to the class II type VI CRISPR system, contains two higher eukaryotes and prokaryotes nucleoside binding domains. It has been confirmed that LwCas13a is a novel CRISPR nuclease with RNA-targeted cleavage activity.
Cat. No.: Cas13a-100 (for 100pmol)
Cat. No.: Cas13a-1k (for 1000pmol)
When LwCas13a recognizes and cleaves the target RNA under the guidance of guide RNA, its "accessory cleavage" activity is activated, which can efficiently cleave non-specific single-stranded RNA (ssRNA) in the reaction system. By designing ssRNA probes with fluorescent groups or other markers at both ends, CRISPR/Cas13a can detect RNA template and amplify the signal, to realize the detection of the target. The system has high sensitivity and strong specificity.
Real-time Fluorescent Detection
Colloidal gold chromatography
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